poxet 60mg is Cyclic GMP is inactivated by the enzyme PDE5 or phosphodiesterase type-5. By blocking this enzyme, Dapoxetine increases cyclic GMP levels and thus improves erection. The main advantage of dapoxetine and other PDE5 inhibitors is that they only work in the presence of s ** all stimulation. Men should take this medicine 30 minutes before sexual intercourse. The effect of this medicine lasts for 24 hours. This medicine will be available on our Trustableshop And 20% discount will be given on the first order.